Table 3 Expression levels of genes involved in ergosterol biosynthesis
ORF | Gene | MA-R4 xylose/glucose (C1) | Glucose MA-R4/MA-B4 (C4) | Description | ||
|---|---|---|---|---|---|---|
(C1-1) | (C1-2) | (C4-1) | (C4-2) | |||
YPL028W | ERG10 | -9.74 | -11.19 | 4.26 | 3.00 | Acetyl-CoA C-acetyltransferase |
YML126C | ERG13 | -9.74 | -11.19 | 4.03 | 3.65 | 3-Hydroxy-3-methylglutaryl-CoA synthase |
YML075C | HMG1 | -6.92 | -7.35 | 6.03 | 6.54 | 3-Hydroxy-3-methylglutaryl-CoA reductase |
YMR208W | ERG12 | -3.62 | -4.78 | 3.76 | 3.87 | Mevalonate kinase |
YMR220W | ERG8 | -4.50 | -3.45 | 2.11 | 2.28 | Phosphomevalonate kinase |
YNR043W | MVD1 | -9.39 | -10.02 | 2.95 | 3.52 | Mevalonate pyrophosphate decarboxylase |
YPL117C | IDI1 | -2.85 | -3.72 | 2.70 | 2.54 | Isopentenyl diphosphate isomerase |
YJL167W | ERG20 | -6.65 | -5.63 | 3.94 | 2.73 | Farnesyl pyrophosphate synthetase |
YHR190W | ERG1 | -14.58 | -9.67 | 6.22 | 3.79 | Squalene epoxidase |
YHR072W | ERG7 | -5.16 | -5.59 | 2.36 | 3.24 | Lanosterol synthase |
YHR007C | ERG11 | -11.73 | -9.61 | 6.15 | 4.27 | Lanosterol 14-α-demethylase |
YGR060W | ERG25 | -6.56 | -7.09 | 6.17 | 5.99 | C-4 methyl sterol oxidase |
YGL001C | ERG26 | -3.79 | -3.71 | 4.95 | 4.28 | C-3 sterol dehydrogenase |
YML008C | ERG6 | -4.50 | -4.41 | 2.72 | 2.47 | Delta-24-sterol C-methyltransferase |
YMR202W | ERG2 | -21.42 | -14.46 | 4.95 | 3.73 | C-8 sterol isomerase |
YLR056W | ERG3 | -8.00 | -9.96 | 4.17 | 4.34 | C-5 sterol desaturase |
YMR015C | ERG5 | -4.08 | -4.95 | 4.55 | 6.70 | C-22 sterol desaturase |