In silico profiling of Escherichia coli and Saccharomyces cerevisiae as terpenoid factories

Table 2 Comparison of theoretical maximal IPP yields with published terpenoid yields (given as C-mol/C-mol)

Organism	Pathway	Carbon source	Maximum IPP yield (this study)	Experimental IPP yield estimated from published yield
E. coli	DXP	glycerol+	0.79	0.04 [59]
E. coli	DXP	glycerol+	0.79	0.06 [14]
E. coli	DXP + MVA	glycerol+	0.79	0.04 [60]
S. cerevisiae	MVA	glucose+	0.53	0.003 [61]
S. cerevisiae	MVA	glucose+	0.53	0.00006 [62]
S. cerevisiae	MVA	galactose	0.53	0.004 [30]
S. cerevisiae	MVA	glucose	0.53	0.0052 [31]
S. cerevisiae	MVA	glucose	0.53	0.01 [8]
S. cerevisiae	MVA	glucose&ethanol	0.53/0.68	0.06 [8]
S. cerevisiae	MVA	ethanol	0.68	0.19 [8]

Experimental yields of sesquiterpenoids are partly estimated and converted into IPP yields (only to that part of IPP that has been converted to the respective terpenoid); + indicates complex media.

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