Figure 1
From: Over-expression and characterization of NS3 and NS5A of Hepatitis C virus genotype 3a
Percentage sequence identities between NS3 [A] and NS5A [B] proteins of various genotypes of hepatitis C virus. The phylogenetic trees and percent identity were derived from alignments of amino acid sequences of NS3 and NS5A proteins using the program ClustalX, version 1.83. Percent identity of NS3/3a and NS5A/3a to proteins of other genotypes is indicated. The tree was drawn using the TreeView program. [A] The phylogenetic tree includes: NS3/3a (NCBI GenBank acc. no. AFJ79449), NS3/3b (BAA08372; Amino acids 1035–1665), NS3/2a (BAB32872.1; Amino acid 1031–1661), NS3/2b (BAB08107; Amino acid 1031–1661)), NS3/1a (AAB66324; Amino acid 1027–1657), NS3/1b(BAC54896; Amino acid 1027–1657). [B] The phylogenetic tree includes: NS5A/3a (AFJ79451), NS5A/3b (BAA08372; Amino acid 1981–2432), NS5A/2b (AAF59945; Amino acid 1977–2442), NS5A/2a (AAF01178; Amino acid 1977–2442), NS5A/1a (AAB66324; Amino acid 1973–2420), NS5A/1b (AAC15725; Amino acid 1973–2419).