Table 4 Kinetic binding constants of P. pastoris produced anti-HER2
Samples | Description | ka (1/M*s) | kd (1/s) | KD (nM) | Ave. KD (nM) |
|---|---|---|---|---|---|
YGLY27431 | OCH1 wild-type, diploid | 4.0E + 4 | 1.9E-4 | 4.7 | 4.63 |
YGLY27432 | OCH1 wild-type, haploid | 4.4E + 4 | 1.8E-4 | 4.2 | |
YGLY27435 | GS2.0, diploid | 4.1E + 4 | 2.2E-4 | 5.3 | |
YGLY27436 | GS2.0, haploid | 3.9E + 4 | 1.7E-4 | 4.3 |