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Figure 1 | Microbial Cell Factories

Figure 1

From: Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli

Figure 1

Biosynthetic pathways of fatty alcohol. The nodes we selected for metabolic engineering are marked in bold. The real lines represent the native pathways of E. coli, while the broken line shows a nonnative pathway of the host. The actual genes used for each step are shown in italics. PD: pyruvate dehydrogenase; ACC: acetyl-CoA carboxylase; FAS: fatty acid synthase; ACP: acyl carrier protein; TE: thioesterase (‘tesA and BTE); ACS: acyl-CoA synthase (fadD, yngl and FAA2); FAR: fatty acyl-CoA reductase (FAR, acr1 and CER4).

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