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Figure 8 | Microbial Cell Factories

Figure 8

From: Methods to optimize myxobacterial fermentations using off-gas analysis

Figure 8

OCQ of a repeated batch cultivation of Chondromyces strain SBCm002. The pO2 was maintained via aeration and the stirring rate was kept constant, resulting in an increase of CO2 and decrease of O2 in the off-gas once respiratory activity decreased. The resulting OCQ curves are highly specific and a lower threshold of this value was used to trigger automated media exchange and metabolite capturing. The culture was maintained for 22 days with approximately 1.5 media replacements daily.

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