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Table 2 Copy number variation between the S288C and CEN.PK113-7D genomes was estimated by mapping CEN.PK and S288C reads to the S288C genome using BWA [45]

From: De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology

CNV S288C coordinates

    

CHR

start

end

p -value

Log2 (CEN.PK/S288C)

CEN.PK CHR

Amplified Genes

VII

1064291

1068431

1.01 × 10-100

0.86

VII, III, XI

BIO2, IMA1

XV

849425

850253

1.63 × 10-21

0.86

XV, VI

RDL1, RDL2

II

805955

808853

3.92 × 10-76

0.89

II, III

MAL32, YBR300C

II

801609

805541

6.79 × 10-110

0.93

II, III

MAL33, MAL31, MAL32, YBR298C-A

III

90771

93253

2.15 × 10-87

1.07

?

LEU2, NFS1

VIII

553415

556313

2.81 × 10-138

1.27

VIII, XI

PHO12, IMD2

  1. Read depth ratios and p-values were calculated using CNV-seq [46]. Regions with a significantly higher read depth in the CEN.PK113-7D genome are reported in this table.