Figure 4From: Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiaeSesquiterpene yield in a two-phase partitioned glucose limited aerobic chemostat. α-Santalene and farnesol yield in Cmmol (Cmmol glucose)-1. Strains SCIGS28 (tHMG1↑), SCIGS29 (+ P HXT1 -ERG9, lpp1 Δ), SCIGS30 (+ dpp1 Δ) were cultivated at dilution rate D = 0.05 h-1 and D = 0.1 h-1. Strains SCIGS31 (+ gdh1 Δ), SCIGS24 (+ERG20↑, GDH2↑), SCIGS25 (+ upc2-1↑, tHMG1↑) were cultivated at dilution rate D = 0.05 h-1. Error bars represent the standard deviation from three independent cultivations.Back to article page