Current status and emerging role of glutathione in food grade lactic acid bacteria

Pophaly, Sarang Dilip; Singh, Rameshwar; Pophaly, Saurabh Dilip; Kaushik, Jai K; Tomar, Sudhir Kumar

doi:10.1186/1475-2859-11-114

Microbial Cell Factories

Table 1 Glutathione concentration in food grade LAB and some related Gram positive bacteria

From: Current status and emerging role of glutathione in food grade lactic acid bacteria

Organism	Possible/ Proposed mode	Glutathione concentration	Medium	Reference
S. thermophilus ATCC 19258	Synthesis	5.7 μmol/g dry weight	Trypticase soy broth	[28]
S. thermophilus S6	ND^*	43.5 nmol/mg	Elliker broth	[18]
S. thermophilus ST2	ND^*	39.2 nmol/mg	Elliker broth	[18]
S. thermophilus MB410	ND^*	10.3 nmol/mg	M-17 broth	[21]
S. thermophilus MB426	ND^*	19.4 nmol/mg	M-17 broth	[21]
S. agalactiae ATCC 12927	Synthesis	11 μmol/g dry weight	Trypticase soy broth	[28]
S. agalactiae 2603 V/R	Synthesis	327 nmol/mg protein	CDM^***	[6]
E. faecalis ATCC 29212	Synthesis	1.8 μmol/g dry weight	Todd Hewitt medium^***	[28]
E. faecalis JH2-2	Synthesis	5.1 μmol/g dry weight	Trypticase soy broth
E. faecium ATCC 6569	ND^*	1.6 μmol/g dry weight	Trypticase soy broth
E. faecalis	Synthesis	78 nmol/mg protein	CDM^***	[32]
E. faecium	Synthesis	189 nmol/mg protein	CDM^***	[32]
Lc. lactis subsp. cremoris ATCC 19257	ND^*	26.3 nmol/mg	M-17 broth	[21]
Lc. lactis subsp. diacetylactis MB447	ND^*	10.5 nmol/mg	M-17 broth	[21]
Lc. lactis	ND^*	0.358 μg/mg protein	Trypticase soy broth	[22]
Lc. lactis ssp. cremoris Z8	Synthesis^?	51.4 nm/mg	Elliker broth	[18]
Leu. mesenteroides ssp. cremoris CAFT9	ND^*	12.6 nmol/mg	APT
Leu. mesenteroides ssp. cremoris ATCC 19254	ND^*	11.4 nmol/mg	MRS
Lc. lactis ssp. cremoris Z8	Synthesis^?	15 nmol/mg	Milk
Lc. lactis	Synthesis^?	4.6 μmol/g	Trypticase soy broth	[4]
Lc. lactis (genetically engineered strain)	Synthesis	358 nmol/mg	CDM^***	[23]
Lc. lactis subsp. cremoris SK 11	Import	10.56 nmol/mg protein	M17 broth	[20]
Lc. lactis subsp. lactis NIZO B89	Import	4.95 nmol/mg protein	M17 broth
Lc. lactis subsp. lactis NIZO B93	Import	9.13 nmol/mg protein	M17 broth
Lb. helveticus CNRZ 32	ND^*	6.2 nm/mg	APT broth	[18]
Lb. casei	Import	0.05 μmol/g	Lactobacillus broth	[4]
Lb. casei HY 2782	ND^*	25.15 μmol/g	MRS broth	[34]
Lb. acidophilus DSMZ 23033	ND^*	4.5 nmol/mg	MRS broth	[21]
Lb. acidophilus	ND^*	0.14 nmol/mg protein	MRS broth	[41]
Lb. salivarius	ND^*	0.11 nmol/mg protein	MRS broth
Lb. casei W56	ND^*	0.09 nmol/mg protein	MRS broth
Lb. rhamnosus	ND^*	~ 14 μmol/g	MRS broth	[34]
Lb. plantarum	ND^*	~ 14 μmol/g	MRS broth	[34]
Lb. plantarum LP1	ND^*	2.7 nmol/mg	MRS broth	[21]
Lb. salivarius	Import/ synthesis^?	~0.5 nmol/mg protein	MRS broth^**	[40]
Lb. salivarius	Import	~22 μmol/10¹² cells	BHI broth	[111]
Lb. fermentum ME-3	Import/ synthesis^?	20 nmol/mg protein	Milk	[36]
Lb. fermentum ME-3	Import/ synthesis^?	9.95 μg/ml	MRS broth	[37]
Lb. fermentum 5716	ND^*	1.4 mM/ ml media	MRS broth	[39]
Lb. reuteri ATCC 23272	Import	~20 mg/g dw	MRS broth^**	[43]
Lb. reuteri ATCC 23272	Import	~15 mg/g dw	MRS broth	[43]
B. adolescentis MB238	ND^*	0.238 μg/mg	MRS broth	[22]
B. breve MB233	ND^*	0.258 μg/mg	MRS broth
B. longum MB243	ND^*	0.333 μg/mg	MRS broth
B. adolescentis B660	ND^*	0.288 μg/mg	MRS broth
B. bifidum W23	ND^*	0.37 nm/ mg	MRS broth	[41]
B. animalis subsp. lactis DSMZ 23032	ND^*	30.3 nmol/mg	MRS broth	[21]

^*not defined.
^** GSH supplemented to medium.
^***Medium devoid of glutathione (either by treating with γ-glutamyl transpeptidase or using chemically defined medium).
^? Contradictory report with respect to present available information.

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ISSN: 1475-2859

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