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Table 3 Results of dynamic fed batch cultivations of different P. pastoris strains based on qs.

From: A fast approach to determine a fed batch feeding profile for recombinant Pichia pastoris strains

  KM71H KM71H HRPa KM71H PDI HRP CBS7435 HRP SMD1168H GalOx
Δtimeadapt Fedbatch [h] 5.5 9.7 10.4 9.2 5.3
qs max determined in batch experiments
[mmol·g-1·h-1]
1.94 ± 0.19 2.00 ± 0.21 1.08 ± 0.10 1.54 ± 0.15 2.62 ± 0.26
qs reached without methanol accumulation
[mmol·g-1·h-1]
1.79 ± 0.18 1.92 ± 0.19 1.22 ± 0.12 1.64 ± 0.16 2.44 ± 0.24
qp maxb
[U·g-1·h-1]
- 11.0 ± 1.10 7.09 ± 0.10 6.48 ± 0.65 139 ± 13.9
  1. a data taken from [18]
  2. b representing the maximum value determined out of all qs periods