Table 3 Results of dynamic fed batch cultivations of different P. pastoris strains based on q_s.

Δtime_{adapt Fedbatch} [h]

5.5

9.7

10.4

9.2

5.3

q_{s max} determined in batch experiments

[mmol·g^-1·h^-1]

1.94 ± 0.19

2.00 ± 0.21

1.08 ± 0.10

1.54 ± 0.15

2.62 ± 0.26

q_s reached without methanol accumulation

[mmol·g^-1·h^-1]

1.79 ± 0.18

1.92 ± 0.19

1.22 ± 0.12

1.64 ± 0.16

2.44 ± 0.24

q_{p max}^b

[U·g^-1·h^-1]

-

11.0 ± 1.10

7.09 ± 0.10

6.48 ± 0.65

139 ± 13.9