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Figure 3 | Microbial Cell Factories

Figure 3

From: Virus-like particle production with yeast: ultrastructural and immunocytochemical insights into Pichia pastoris producing high levels of the Hepatitis B surface antigen

Figure 3

Close-up views of P. pastoris GS115 producing HBsAg. Transmission electron micrographs of single cells are shown in A and B. A1 is enlarged from the boxed area of A localized in the 'irregular cloud-shaped area' (*), and the square-boxed insert of A1 shows a negatively stained reconstructed VLP with the same scale as in A1. A2 represents the corresponding inverse fast Fourier transformation (iFFT) of area A1. The 6 nm layer-spacing is indicated by arrows in A1 and A2. B1 is enlarged from boxed area in B; B2 represents the corresponding inverse fast Fourier transformation (iFFT) of area B1. Abbreviations as specified in Figure 1.

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