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Fig. 9 | Microbial Cell Factories

Fig. 9

From: Transcriptomics aids in uncovering the metabolic shifts and molecular machinery of Schizochytrium limacinum during biotransformation of hydrophobic substrates to docosahexaenoic acid

Fig. 9

Schematic illustration for hydrophobic waste oil assimilation in thraustochytrid SR21. (The red lines highlight the biosynthetic steps upregulated in the presence of HS, black line denotes the route followed by glucose alone, whereas blue line denotes the process common in both “de novo” and “ex-novo” cultivation) created with Biorender.com. gk: glycerol kinase, tpi: triose phosphate isomerase, accase: acetyl-CoA carboxylase, pk: pyruvate kinase,, pdh: pyruvate dehydrogenase, pdc: icl: isocitrate lyase, icdh: isocitrate dehydrogenase, me: malic enzyme, des: desaturases; pdat: phospholipid: diacylglycerol acyltransferase, arf: ADP-ribosylation factor, fat: fatty acid transporter, acs: acyl-CoA synthetase, acox: acyl-CoA oxidase, acad: acyl-CoA dehydrogenases, kat: ketoacyl CoA-thiolase, N-WASP: Wiskott-Aldrich syndrome protein PL: phospholipids, G6P: glucose 6-phosphate, F6P: fructose-6-phosphate, GAP: glyceraldehyde-3-phosphate, DHAP: dihydroxyacetone phosphate, PEP: phosphoenol pyruvate, LPA: lysophosphatidic acid, PA: phosphatidic acid, DAG: diacylglycerol, TAG: triacylglycerol

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