High cell density sequential batch fermentation for enhanced propionic acid production from glucose and glycerol/glucose mixture using Acidipropionibacterium acidipropionici

Table 1 Sequential batch fermentation of glucose using A. acidipropionici DSM 4900 with cell recycle

N-source	Batch 1	Batch 2	Batch 3	Batch 4	Batch 5	Batch 6	Batch 7	Batch 8	Batch 9
N-source	HTPJ (1X), 0.5 mg/L biotin
Q_p (g/L.h)	0.18	0.33	0.55	0.75	1.05	0.76	0.80	0.67	1.15
Q_s (g/L.h)	0.35	0.61	1.08	1.47	2.19	1.68	1.81	1.22	2.57
Y (g/g)	0.53	0.57	0.57	0.55	0.57	0.57	0.57	0.59	0.55
Y (mol/mol)	1.21	1.33	1.24	1.24	1.16	1.10	1.08	1.32	1.09
r_P (g_PA/g_X.h)	0.017	0.023	0.033	0.025	0.033	0.022	0.020	0.021	0.028
Initial CDW (g/L)	0.24	10.21	17.42	18.30	30.45	37.84	39.89	33.60	37.19
Final CDW (g/L)	10.69	14.49	16.84	29.57	31.62	35.28	39.89	31.48	40.70
Initial PA (g/L)	0.00	1.13	1.90	1.30	2.88	3.69	3.48	3.45	3.22
Final PA (g/L)	18.01	20.36	21.17	21.27	18.79	18.16	17.93	17.51	18.49
Final AA (g/L)	3.07	4.91	4.73	4.58	3.87	4.11	4.48	4.24	4.36
Final SA (g/L)	3.30	5.05	5.48	6.17	5.36	4.82	4.36	4.05	4.22
PA/AA (mol/mol)	4.75	3.36	3.63	3.76	3.93	3.58	3.24	3.35	3.44
PA:SA:AA (g)	100:18:17	100:25:24	100:26:22	100:29:22	100:29:27	100:27:23	100:24:25	100:23:24	100:23:24

Production of propionic acid from glucose using A. acidipropionici DSM 4900 for 9 sequential batches with cell recycling. The concentrations of PA, SA, AA, and biomass, as well as the fermentation kinetics are presented

ISSN: 1475-2859