Fig. 2

Kinetics of biomass growth (circles) and recombinant protein production (triangles) of RBD-P (filled symbols) and RBD (open symbols) from SARS-CoV-2 by E. coli BL21 (DE3), in shake flasks (A) and in bioreactors (B). Data presents the average and standard deviation of the cultures carried out at least in triplicate. Induction with IPTG started after 6 h of culture. Inset figures are logarithmic biomass growth. Glucose consumption was also presented for shake flasks (C) and bioreactors (D) cultures