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Fig. 7 | Microbial Cell Factories

Fig. 7

From: Quantifying microbial robustness in dynamic environments using microfluidic single-cell cultivation

Fig. 7

Robustness across populations as a description of population heterogeneity. (a) Visual representation of R(p) computation. R(p) denotes how homogeneous a function is within the same population at a single time point (t1, t2 or t3). Elevated R(p) describes a homogeneous function within the population, low R(p) a heterogeneous function. Here, the mean and standard deviation of a function among all cells (A, B, C, D) at each time point (t1, t2, t3) were calculated and used to compute R(p) for each time point. (b) R(p) of intracellular ATP levels for all tested oscillation frequencies. Standard deviations represent the distribution across triplicates (chambers). See Additional file 2: Figure S12 for all functions and distribution of R(p) at each time point (in violin plots)

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