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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Quantifying microbial robustness in dynamic environments using microfluidic single-cell cultivation

Fig. 3

Population response and performance in dynamic feast-starvation oscillations. Error bars represent the standard deviation of triplicates (three chambers). (a) Line plots showing growth curve, budding ratio, and intracellular ATP level over the course of 12 h. The black vertical line indicates the beginning of glucose oscillation after 4 h of cultivation. Full 24-h screening data are available in Additional file 2: Figure S1. (b) Average specific growth rate, budding ratio, intracellular ATP level, area, and circularity of cells exposed to feast-starvation oscillations. Student’s t-test was performed to assess statistical differences between each feast-starvation oscillation frequency and the control condition (constant feast); *p ≤ 0.05, **p ≤ 0.01

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