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Fig. 9 | Microbial Cell Factories

Fig. 9

From: Construction of recombinant Lactococcus expressing thymosin and interferon fusion protein and its application as an immune adjuvant

Fig. 9

Comparison of cytokine levels and T lymphocyte proliferation activity after immunization with recombinant lactic acid bacteria r-L. lactis-Tα1-IFN. (a, b, c, and d) Serum cytokines interferon-γ, interleukin (IL)-4, IL-2, and IL-10 are detected in each group on post-immunization days 3, 7, and 14, respectively. (e) T lymphocyte proliferative activity analysis of PMA + Ionomycin activated peripheral blood mononuclear cells. Data are presented as mean ± standard deviation. Statistical significance was set at *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Microbial Cell Factories

ISSN: 1475-2859

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