Table 1 Examples of recombinant proteins produced in S. cerevisiae

Medicinal Proteins

Antithrombin III

312 mg/L

Fed-batch fermentation in 5 L bioreactor

[30]

Human pancreatic ribonuclease

0.1–0.2 mg/L

Batch fermentation in shake flask

[31]

Transferrin

2.33 g/L

Fed-batch fermentation in 10 L bioreactor

[32]

α-tropomyosin

20 mg/L

Batch fermentation in shake flask

[33]

Human caseinomacropeptide

2.5 g/L

Fed-batch fermentation in 5 L bioreactor

[34]

Human haemoglobin

18% of the total cell protein

Batch fermentations in 1 L bioreactors

[35]

α-Amyrin

11.97 mg/L

Batch fermentation in shake flask

[36]

Food Proteins

Brazzein

9 mg/L

Batch fermentation in shake flask

[37]

L-(+)-ergothioneine

598 ± 18 mg/L

Fed-batch fermentation in 1 L bioreactor

[38]

Glutathione

7.3 mg/L

Batch fermentation in shake flask

[39]

Sweet protein

0.41 g/L

Batch fermentation in shake flask

[40]

Industrial Enzymes

Laccase₃

1176.04 U/L

Batch fermentation in shake flask

[41]

Lipase

11,000 U/L

Fed-batch fermentation in 5 L bioreactor

[42]

Cellulases

0.6–2.0 g/L

Batch fermentation in shake flask

[43]

Dextranase

58.45 U/mL

Batch fermentation in shake flask

[44]

Glucoamylase

2425 nkat/g dry cell weight

Batch fermentation in shake flask

[45]

Levansucrase

50 U/mL

Fed-batch fermentation in 5 L bioreactor

[46]

Cutinase

29.7 U/mL

Fed-batch fermentation in 3 L bioreactor

[47]

Kex₂ protease

20 mg/L

Batch fermentation in shake flask

[48]

Collagenases

68 U/mL

Batch fermentation in shake flask

[49]

Inulinase

34.6 U/mL

Batch fermentation in shake flask

[50]

Cellobiohydrolase

0.58 U/g DCW

Batch fermentation in shake flask

[51]