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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Glycylglycine promotes the solubility and antigenic utility of recombinant HCV structural proteins in a point-of-care immunoassay for detection of active viremia

Fig. 6

The clinical utility of the denatured and soluble antigens-based immunoassays. A, B ROC curve analysis of S/Co values of viremic/non-viremic sera assessed against denatured and soluble antigens showed an area under the curve (AUC) of 0.8875 and 0.9362, respectively (P < 0.0001/each). C, D: The best S/Co cutoff values for predicting active viremia was 1.03 and 2.75, respectively, showing 80.08, 94.14% and 81.58, 82.11% PPV and NPV, respectively, with 87.64 and 85.42, 87.64% and 75.24, 91.23% sensitivity and specificity, respectively

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