Table 1 Simulated yields of optimal target production for different scenarios of metabolic activity. The yield is calculated as the production rate of the respective product divided by the methanol uptake uptake rate (both mmol/gDW/h). ‘Ref’ refers to a simulation without special constraints, ‘TCA-’ was constrained to inhibit circular TCA cycle flux, in ‘TCA+’ flux was forced to enter circular TCA cycle, ‘GlxStd’ represents a flux distribution forced into the standard glyoxylate shunt, and ‘GlxVar’ represents a flux distribution with forced fluxes without malate dehydrogenase activity. The identity of the reactions within the reaction network ist sketched in the SI the Figure S1

From: Methanol bioconversion into C3, C4, and C5 platform chemicals by the yeast Ogataea polymorpha