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Fig. 7 | Microbial Cell Factories

Fig. 7

From: Methanol bioconversion into C3, C4, and C5 platform chemicals by the yeast Ogataea polymorpha

Fig. 7

Acetone titer, final optical density, and methanol concentration for O. polymorpha strains overexpressing heterologous genes for acetone synthesis. O. polymorpha strains either overproducing PpAdc(p), CtfAB(p), and ThlA(p) (ACT) or PpAdc(p), YbgC(p), and ThlA(p) (AYT). Strains were cultivated in 250 mL air-tight serum bottles with 25 mL Verduyn medium + 4 g/L (0.5% (v/v)) methanol. For the ACT strain, an additional condition was analyzed where 1.5 g/L acetate were added to the medium (+ Acetate). The headspace consisted either of 100% air (A) or of 50% air and 50% pure oxygen (B). Error bars represent the standard deviation of biological triplicates

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