Microbial Cell Factories

Table 2 The number of solutions in iJR904 (Strain0 in CM2 cultivation medium)

From: FastKnock: an efficient next-generation approach to identify all knockout strategies for strain optimization

Order of reaction knockout	Strain0 in CM2
	succinate		2-oxoglutarate		D-lactate
	v_max^*	v_grnt^**	v_max	v_grnt	v_max	v_grnt
Single	2	1	0	0	0	0
Double	58	27	0	0	10	7
Triple	887	416	0	0	308	228
Quadruple	10,090	4794	0	0	4941	3790
Quintuple	98,300	48,693	29	0	58,481	13,639

^*v_max: maximum production rate (mmol.gDW⁻¹ h⁻¹)
^**v_grnt: guaranteed production rate (mmol.gDW⁻¹ h⁻¹)

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ISSN: 1475-2859

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