Camptothecin bioprocessing from Aspergillus terreus, an endophyte of Catharanthus roseus: antiproliferative activity, topoisomerase inhibition and cell cycle analysis

Table 3 ANOVA for selected factorial model, Analysis of variance table [Partial sum of squares—Type III]

Source	Sum of squares	df	Mean square	F-value	Prob > F
Model	92,291.32	6	15,381.89	13.67	< 0.0001	Significant
B-Yeast extract	7123.86	1	7123.86	6.33	0.0258
G-Glutamine	6119.01	1	6119.01	5.44	0.0364
J-Tryptophan	13,625.26	1	13,625.26	12.11	0.0041
O-Incubation time	38,015.14	1	38,015.14	33.79	< 0.0001
R-CaCl₂	10,731.67	1	10,731.67	9.54	0.0086
T-Methyl jasmonate	16,676.38	1	16,676.38	14.82	0.002
Residual	14,625.95	13	1125.07
Cor total	1.07E + 05	19

ISSN: 1475-2859