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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Camptothecin bioprocessing from Aspergillus terreus, an endophyte of Catharanthus roseus: antiproliferative activity, topoisomerase inhibition and cell cycle analysis

Fig. 4

Antimicrobial activity of the extracted A. terreus CPT towards CPT producing and non-producing fungi. The CPT spots were scrapped-off from the TLC silica gel plates, eluted, and different concentrations of the CPT (5, 10 and 15 μg/ml) was applied to the tested fungal cultures, incubated for 5 days, then the diameter of the inhibition zone was measured. After A The panel of CPT-producing fungi (A. terreus, A. fumigatus, A. flavus, A. oryzae). B The panel of non CPT-producing fungi (Rhizopus sp, Mucor sp, Trichoderma sp, and Penicillium sp). C The diameter of the inhibition zone of the CPT producing and non CPT-producing fungi by the purified A. terreus CPT

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