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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Camptothecin bioprocessing from Aspergillus terreus, an endophyte of Catharanthus roseus: antiproliferative activity, topoisomerase inhibition and cell cycle analysis

Fig. 1

Screening for CPT production by the fungal endophytes of Catharanthus roseus. After incubation, CPT was extracted and screened by TLC and the yield of the most promising CPT producing isolates was quantified by HPLC. A Morphological view of the leaves and flowers of C. roseus. B Selected CPT producing endophytic fungal isolates. C, TLC profile of the recovered endophytic fungal isolates for CPT screening. Five μl of each sample were spotted to the TLC plate, compared to the authentic CPT (5 μl of at 50 μg/ml). D Yield of CPT from the most potent fungal isolates quantified by Image J Software Package. E HPLC chromatogram of the highest CPT producing isolates 14, normalized to the sample # 1, as non CPT-producers

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Microbial Cell Factories

ISSN: 1475-2859

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