Fig. 7

Fold-differences in viral RNAs recovered from G-PEN-HuscFv34-6× His treated-infected cells compared to medium treated-infected cells. Vero E6 cells were infected with Betacoronavirus, i.e., SARS-CoV-2 (Wuhan wildtype or B1.1.529 Omicron variant) while Vero cells were infected with flaviviruses (DENV serotypes 1–4, ZIKV) or Alphacoronavirus (PEDV) for 1 h. The fluids in wells were discarded and the infected cells were treated with G-PEN-HuscFv34-6× His (0.5 μM) for 18 h (SARS-CoV-2 and PEDV) or 48 h (DENV and ZIKV). Infected cells in medium alone served as controls. The cells were harvested for RNA extraction and the viral RNAs were quantified by qRT-PCR. ∗∗∗∗, p < 0.0001