Fig. 8
From: Computational analysis of protein synthesis, diffusion, and binding in compartmental biochips
Qualitative comparison of experimental results and simulations for different trap patterns. a, c, e Fluorescence signals of bound and unbound (\(b+u\)) GFP synthesized in a quasi-twodimensional, silicon-based expression system recently introduced [26] for different trap patterns (purple bars) 1 h after start of synthesis. Signal normalized to the respective maximum value measured after 2 h. b, d, f Simulations of GFP synthesis, diffusion and binding in a 100-box system with synthesis sites being located at boxes \(i_\mathrm{syn} = 12,\,...,19\) (gray boxes), trap patterns as in a, c and e, respectively, and at simulation time \(t = 39\cdot 10^3\Delta t\). Number of bound and unbound GFP molecules is normalized to the respective maximal number of traps per box