Systems biology of industrial oxytetracycline production in Streptomyces rimosus: the secrets of a mutagenized hyperproducer

Table 1 Expression of selected genes associated with cell metabolism and morphology

Locus tag	Annotation	Fold-change
SRIMR7_14410	Chitinase D	2.2
SRIMR7_38545	Poly-ß-1,6-N-acetylglucosamine synthase	1.8
SRIMR7_12545	Chitinase 63	1.7
SRIMR7_24075	Murein DD-endopeptidase, mepM	1.4
SRIMR7_11730	Exochitinase	1.3
SRIMR7_01200	Chitinase C	1.1
SRIMR7_38525	Chitinase D	1.1
SRIMR7_01835	Chitinase	1.1
SRIMR7_25310	Glycerophosphotransferase, tagF	−1.1
SRIMR7_25990	Cellulose synthase (UDP-forming)	−1.3
SRIMR7_37765	Chitinase class I	−1.3
SRIMR7_25305	Putative glycosyltransferase, epsJ	−1.4
SRIMR7_38620	Putative poly(glycerol-phosphate) alpha-glucosyltransferase, tagE	−1.5
SRIMR7_25250	Teichoic acid export, ATP binding protein, tagH	−5.7
SRIMR7_25255	Teichoic acid export, ATP binding protein, tagG	−5.8

The data are taken from the transcriptome analysis of S. rimosus ATCC 10970 and its mutagenized derivative HP126 (Fig. 2), sampled during the major production phase (24 h). n = 3

ISSN: 1475-2859