Fig. 7
From: Multivalent poultry vaccine development using Protein Glycan Coupling Technology
χ7122 pgl expressing G-NetB(10) from pEXT20 fails to substantially reduce Campylobacter colonisation. a Experimental design; b Strain colonisation levels in the caeca of vaccinated chickens at days 21, 28 and 35. Retrieved vaccine strains were NalR, KanR only, indicating loss of AmpR pEXT20-G-NetB(10) plasmid in vivo. c Colonisation levels of C. jejuni strain M1 in the caeca of vaccinated chickens one week after challenge. Colonisation levels of the caecum from either the live vaccine (b) or C. jejuni M1 (c) are expressed as log10 CFU/g. Statistically significant reductions are highlighted with * indicating p-values < 0.05 (Mann–Whitney U test). Data are represented as median values with 95% confidence intervals