Fig. 1

N- and O-glycan sulfation. N- and O-glycans can be chemically modified with sulfate. Sulfation typically occurs at position C6 on GlcNAc, GalNAc, Gal or Man (orange highlight), at position C4 on GalNAc (grey highlight) or at position C3 on Gal (purple highlight). Examples of sulfated O-glycans from human glycoproteins (1, 2, 3 and 6) [15,16,17,18], and sulfated N-glycan structures from Influenza virus (4), human peripheral blood cells (5), human Tamm-Horsfall glycoprotein (7), human pituitary hormones (8) [14] and Panulirus interruptus hemocyanin (9) [19] are shown. Glycans are represented using SNFG nomenclature [69]