Authors, Years | Agents | Participants | Study design | Outcome | References |
---|---|---|---|---|---|
Tzeng et al., 2018 | Acyclovir, Famciclovir, Gangciclovir, Valacyclovir, Valganciclovir | 8362 | Cohort study | Decreased risk of dementia | [77] |
Devanand et al., 2020 | Valacyclovir | 130 | Randomized, double-blind, controlled trial | NA | [81] |
Loeb et al., 2004 | Rimfapicin, Doxycycline | 101 | Randomized, triple-blind, controlled trial | Lower cognitive decline | [83] |
Kountouras et al., 2009 | Amoxicillin, Clarithromycin | 56 | Cohort study | Cognitive function improvement | [89] |
Howard et al., 2020 | Minocycline | 554 | Randomized, double-blind, controlled trial | No effect on cognitive function | [94] |
Dominy et al., 2019 | COR388 | 573 | Randomized, double-blind, controlled trial | NA | [95] |