From: Cellulases and beyond: the first 70 years of the enzyme producer Trichoderma reesei
Substance produced | Substrate employed | T. reesei strain background | Genetic alteration | Maximum titer | Reference |
---|---|---|---|---|---|
Ethylene | Wheat straw, cellulose | T. reesei (viride) TL124 | Ethylene forming enzyme of Pseudomonas syringae expressed under the cel7a promoter | 1.06 µl h−1 g−1 dry weight | [169] |
Ethylene | Wheat straw | QM9414 | Ethylene forming enzyme of P. syringae expressed under the cel7a, pgk1 and A. nidulans gpdA promoters | 4.012 nl h−1 l−1 | [170] |
N-acetyl-neuraminic acid | Chitin | QM9414 | Expression of codon optimized N-acetyl glucosamine-2-epimerase from Anabaena sp. and N-acetyl neuramininc acid synthase from Campylobacter jejuni under the pki1 and xyn1 promoters | 13 µg g−1 mycelium | [171] |
Xylitol | Barley straw | QM9414 | Deletion of xylitol dehydrogenase, double deletion of xylitol dehydrogenase and l-arabinitol-4-dehydrogenase | 13.2 g l−1 | [172] |
Xylitol | Xylose and glucose | QM9414 | Knockdown (antisense RNA) of xylulokinase; deletion of xylitol dehydrogenase, overexpression of d-xylose reductase | 3.7 g l−1 | [173] |
Erythritol | Wheat straw | RUT-C30, QM6a | Erythrose reductase expressed under the pki1 and bxl1 promoters | 5 mg l−1 | [174] |