Fig. 4
From: Enhancing full-length antibody production by signal peptide engineering
The effects of signal peptide hydrophobicity on the cellular localization of inclusion bodies. TEM of E. coli expressing pBR-ssSTII0.3-ssSTII1-hu5D5, pBR-ssSTII0.3-ssDsbA1-hu5D5, pBR-ssSTII0.3-ssMalE1-hu5D5, pBR-ssSTII0.3-ssPhoA1-hu5D5, pBR-ssSTII0.3-ssSTII1 S-13L-hu5D5, or pBR-ssSTII0.3-ssDsbA1 L-9S-hu5D5. Black arrows point to the periplasmic space, and the white arrowheads point to the inclusion bodies