Table 2 Point mutations in evolved E1 strains
Name | Description | Evolved strains | ||
|---|---|---|---|---|
E1A | E1B | E1C | ||
Mth1 | Negative regulator of the glucose-sensing signal transduction pathway | A81/D | I85/S | A81/D |
Cit1 | Mitochondrial citrate synthase | P176/Q | M84/V | H175/R |
Hxt2 | High-affinity glucose transporter of the major facilitator superfamily | W466/* | G75/R | W466/* |
Rpd3 | Histone deacetylase, component of both the Rpd3S and Rpd3L complexes | 85F/I | 196A/V | |