Table 2 Comparison of microbial CA and pHCA production parameters and culture conditions
Organism | PAL/TAL | Carbon source | Culture medium | Culture conditions | pHCA (μM) | Q pHCA (μmol/Lh) | CA (μM) | Q CA (μmol/Lh) | Reference |
|---|---|---|---|---|---|---|---|---|---|
E. coli (W3110) | R. glutinis | Glucose | Mineral | 30°C 24 h | 42.4 | 1.76 | 32.9 | 1.37 | [5] |
Baffled Flask | |||||||||
E. coli (DH10B) | R. glutinis | Glucose | Mineral | 30°C 18 h | 280 | 15.5 | 280 | 15.5 | [5] |
Baffled Flask | |||||||||
E. coli(ATCC 31884) | R glutinis | Glucose | Mineral | 30°C 18 h | 150 | 8.33 | 380 | 21.1 | [5] |
Baffled Flask | |||||||||
S. cerevisiae | R. glutinis | Glucose | Mineral | 30°C 48 h | 14.3 | 0.29 | - | - | [5] |
Baffled Flask | |||||||||
E. coli (BL21*AI) | Trichosporon cutaneum | LB | 30°C 16 h | 432 | 27 | 843 | 52.68 | [16] | |
P. putida S12 C1 | Rhodosporidium. toruloides | Glucose | Mineral | 30°C | 224 | 84 (μmol/h*gDCW) | 350 | - | [6] |
Shake flask | |||||||||
P. putida S12 C3 | R. toruloides | Glucose | Mineral | 30°C | 860 | 84 (μmol/h*gDCW) | 70 | - | [6] |
Shake flask | |||||||||
P. putida S12 C3 | R. toruloides | Glucose | Mineral | 30°C | 10,600 | 24 (μmol/h*gDCW) | 150 | - | [6] |
Fed-batch | |||||||||
S. lividans | R. sphaeroides | Glucose | 3% TSB | 28°C | 4755 | 28.5 | - | - | [31] |
5% Triptone | 168 h | ||||||||
P. putida S12 | R. toruloides | Glucose | Mineral | 30°C | - | - | 415 | 12 | [21] |
Shake flask | |||||||||
ON | |||||||||
P. putida S12 | R. toruloides | Glucose | Mineral | 30°C | - | - | 5,000 | 166 | [21] |
Fed-batch | |||||||||
30 h | |||||||||
N2 limitation | |||||||||
P. putida S12 | R. toruloides | Glycerol | Mineral | 30°C | - | - | 5,400 | 108 (60 μmol/h*gDCW) | [21] |
Fed-batch | |||||||||
50 h | |||||||||
N2 limitation | |||||||||
S. lividans | S. maritimus | Glucose | TSB | 28°C | - | - | 540 | 5.62 | [22] |
Shake flask | |||||||||
96 h | |||||||||
S. lividans | S. maritimus | Glucose | TSB | 28°C | - | - | 1417 | 11.8 | [22] |
Triptone | Shake flask | ||||||||
120 h | |||||||||
S. lividans | S. maritimus | Xylose | TSB | 28°C | - | - | 2,024 | 14.05 | [22] |
Triptone | Shake flask | ||||||||
144 h | |||||||||
VPJRg | R. glutinis | Glucose | M9 | 16 h | 91.45 | 5.72 | 196.15 | 12.26 | This work |
VPJAt | A. thaliana | Glucose | M9 | 36 h | - | - | 529.94 | 14.72 | This work |
WPJAt | A. thaliana | Arabinose | M9 | 31 h | - | - | 1,022.36 | 28.4 | This work |
W(pheA−)Rg | R. glutinis | SH | M9 | 16 h | 355.87 | 22.24 | 105.45 | 6.59 | This work |
WPJAt | A. thaliana | SH | M9 | 31 h | - | - | 377.87 | 12.19 | This work |