Figure 1
From: Metabolic engineering of the fungal D-galacturonate pathway for L-ascorbic acid production
Schematic figure of the disrupted fungal D-galUA pathway and the heterologous pathway introduced in A. niger for L-AA biosynthesis: native GaaA (D-galUA reductase), native GaaB (L-galA dehydratase), EgALase (L-galL aldonolactonase from Euglena gracilis ), Smp30 (aldonolactonase from rat functioning in the animal L-AA pathway) and MgGALDH (L-galL dehydrogenase from Malpighia glabra).