Source | Mutation | Remarks | References |
---|---|---|---|
Enzymatic proteins | |||
1-deoxy-D-xylulose 5-phosphate reductoisomerase | |||
Escherichia coli | E231K | 0.24% wild-type kcat | 108 |
Escherichia coli | H153Q | 3.5-fold increase in Km | 108 |
Escherichia coli | H209Q | 7.6-fold increase in Km | 108 |
Escherichia coli | H257Q | 19-fold increase in Km | 108 |
xylulose kinase | |||
Escherichia coli | XylB- mutant | Lack of growth on xylitol | 109 |
Dihydroxyacetone synthase | |||
Hansenula polymorpha | Pex1–6(ts) | Peroxisome-deficient | 110 |
Hansenula polymorpha | Deltapex14 | Lack normal peroxisomes | 111 |
Non-enzymatic proteins | |||
Xylulose-5-phosphate receptor | |||
Mycobacterium tuberculosis | Â | Â | 112 |
Xylulose-5-phosphate trasporter | |||
Arabidopsis sp. | Â | Â | 113 |