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Figure 6 | Microbial Cell Factories

Figure 6

From: Directed evolution of single-chain Fv for cytoplasmic expression using the β-galactosidase complementation assay results in proteins highly susceptible to protease degradation and aggregation

Figure 6

Location of isolated mutations in HuLys11 scFv structure Schematic representation of the HuLys11 scFv (pdb 1BVK). The CDR loops are represented in blue. The side chain of three of the four isolated mutations (see additional file HuLys11aa.txt) are represented in red. The fourth mutation, located in the linker sequence, is not present in the structure.

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