Table 1 Calculated TON for whole-cell bioconversions of E. coli C43(DE3) (pIT2cyp154C5) (pACYCcamAB) and six different steroid substrates at 30°C
From: Selective steroid oxyfunctionalisation by CYP154C5, a bacterial cytochrome P450
Substrate | TON (μmol substrate consumed min-1 μmol-1CYP154C5) |
|---|---|
Pregnenolone (1) | 3.28 ± 0.05 |
Dehydroepinadrosterone (2) | 2.90 ± 0.17 |
Progesterone (3) | 3.33 ± 0.10 |
Androstenedione (4) | 2.15 ± 0.03 |
Testosterone (5) | 0.82 ± 0.01 |
Nandrolone (6) | 1.24 ± 0.15 |