Figure 2From: Identification and physiological characterization of phosphatidic acid phosphatase enzymes involved in triacylglycerol biosynthesis in Streptomyces coelicolorBioinformatic analysis of S. coelicolor PAPs. (A) Sequence alignment of scoLPPs PAP2 domains. The key residues for this catalytic activity are underlined. (B) Phylogenetic tree of LPP enzymes from different organisms. Bootstrap values are shown along the branches. (C) Transmembrane topology prediction of scoLPPs. Numbers represent amino acid position of start and end of the respective transmembrane helix. Location of the catalytic domains is represented with black stars. Sequence accession numbers: atLPP_alfa1 [EMBL:Q9ZU49], atLPP_alfa2 [EMBL:Q9XI60], atLPP_alfa3 [EMBL:Q8LFD1], atLPP_epsilon1 [EMBL:F4J220], atLPP_epsilon2 [EMBL:Q6NQL6], atLPP_gamma [EMBL:Q6NLA5], scLPP1p [EMBL:Q04396], scDPP1p [EMBL:Q05521], hsLPP1 [EMBL:O14494], hsLPP2 [EMBL:O43688], mmLPP1 [EMBL:Q61469], mmLPP2 [EMBL:Q9DAX2], scoLPPα [EMBL:Q9K3P6], scoLPPβ [EMBL:Q9EWX3], scoLPPγ [EMBL:O86624], synLPP [EMBL:Q55398].Back to article page