Figure 4

Patterns of the CCC-Biclusters describing the transcriptional changes occurring in hexose transporter genes (in bold) and selected transcription factors following ammonium supplementation (RF) to the nitrogen-limited fermentation (LF). Two incubation time periods were compared following 80 h of LF fermentation (a control time point): i) after 8 h of incubation following ammonium supplementation (period 1) and ii) after a period of incubation extending from 8 to 24 h following ammonium supplementation (period 2). The transcriptional alterations during the selected periods are shown under parenthesis as U (U pregulation), D (D ownregulation) and N (N o changes registered). The full list of genes present in each bicluster is provided in Additional file 1.