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Figure 1 | Microbial Cell Factories

Figure 1

From: Whole cell biosynthesis of a functional oligosaccharide, 2′-fucosyllactose, using engineered Escherichia coli

Figure 1

The metabolic pathway for GDP- -fucose and 2′-fucosyllactose (2-FL) biosynthesis in recombinant E. coli . The names of enzymes are abbreviated as follows; ManA, mannose 6-phosphate isomerase; ManB, phosphomannomutase; ManC, mannose 1-phosphate guanylyltransferase; Gmd, GDP- d-mannose-4,6-dehydratase; WcaG, GDP-4-keto-6-deoxymannose 3,5-epimerase 4-reductase; FucT2, α-1,2-fucosyltransferase. Pi, GDP and GTP denote phosphate, guanosine 5′-diphosphate and guanosine 5′-triphosphate.

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Microbial Cell Factories

ISSN: 1475-2859

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