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Figure 2 | Microbial Cell Factories

Figure 2

From: Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae

Figure 2

Set-up of the in situ product removal (ISPR) chemostat cultivation process. A stirred tank reactor is operated in continuous cultivation mode as double phase system feeding culture medium (light grey) and organic solvent (dark grey). The product is continuously captured in the organic phase due to its high hydrophobicity. In an integrated downstream step the two phases of the effluent are partitioned in a settler. Subsequently, the product is recovered from the organic phase, which can then be further recycled in the same process. The exhausted medium is discarded.

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