Figure 3From: Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastorisSchematic view of the ergosterol pathway and fluconazole inhibition. Outline of the post-squalene ergosterol biosynthetic pathway illustrating the step inhibited by fluconazole. Dashed arrows indicate no specification of intermediates, and red arrows highlight the genes that are upregulated in the Fab strain in hypoxic conditions.Back to article page