Skip to main content

Articles

Page 48 of 66

  1. Transcriptional engineering has presented a strong ability of phenotypic improvement in microorganisms. However, it could not be directly applied to Actinoplanes teichomyceticus L-27 because of the paucity of end...

    Authors: Haiyong Wang, Liu Yang, Kuo Wu and Guanghui Li
    Citation: Microbial Cell Factories 2014 13:10
  2. In recent years the generation of antibodies by recombinant methods, such as phage display technology, has increased the speed by which antibodies can be obtained. However, in some cases when recombinant antib...

    Authors: Mathias Lindh Jørgensen, Niels Anton Friis, Jesper Just, Peder Madsen, Steen Vang Petersen and Peter Kristensen
    Citation: Microbial Cell Factories 2014 13:9
  3. An industrial approach to protein production demands maximization of cloned gene expression, balanced with the recombinant host’s viability. Expression of toxic genes from thermophiles poses particular difficu...

    Authors: Agnieszka Zylicz-Stachula, Olga Zolnierkiewicz, Katarzyna Sliwinska, Joanna Jezewska-Frackowiak and Piotr M Skowron
    Citation: Microbial Cell Factories 2014 13:7
  4. Corynebacterium glutamicum has large scale industrial applications in the production of amino acids and the potential to serve as a platform organism for new products. This means the demand for industrial proces...

    Authors: Friedrich Käß, Stefan Junne, Peter Neubauer, Wolfgang Wiechert and Marco Oldiges
    Citation: Microbial Cell Factories 2014 13:6
  5. Recent years have witnessed a rising trend in exploring microalgae for valuable carotenoid products as the demand for lutein and many other carotenoids in global markets has increased significantly. In green m...

    Authors: Weiqi Fu, Giuseppe Paglia, Manuela Magnúsdóttir, Elín A Steinarsdóttir, Steinn Gudmundsson, Bernhard Ø Palsson, Ólafur S Andrésson and Sigurður Brynjólfsson
    Citation: Microbial Cell Factories 2014 13:3
  6. Over the recent years the production of Ehrlich pathway derived chemicals was shown in a variety of hosts such as Escherichia coli, Corynebacterium glutamicum, and yeast. Exemplarily the production of isobutyric ...

    Authors: Karsten Lang, Jessica Zierow, Katja Buehler and Andreas Schmid
    Citation: Microbial Cell Factories 2014 13:2
  7. Lipolytic enzymes are commonly used to produce desired flavors in lipolyzed milkfat (LMF) manufacturing processes. However, the choice of enzyme is critical because it determines the final profile of fatty aci...

    Authors: Qing Peng, Xu Wang, Meng Shang, Jinjin Huang, Guohua Guan, Ying Li and Bo Shi
    Citation: Microbial Cell Factories 2014 13:1
  8. Decades of work requiring heterologous expression of eukaryotic proteins have shown that no expression system can be considered as the panacea and the appropriate expression strategy is often protein-dependent...

    Authors: Fabien Debailleul, Cataldo Trubbia, Nancy Frederickx, Elsa Lauwers, Ahmad Merhi, Jean-Marie Ruysschaert, Bruno André and Cédric Govaerts
    Citation: Microbial Cell Factories 2013 12:129
  9. The success of Pichia pastoris as a heterologous expression system lies predominantly in the impressive yields that can be achieved due to high volumetric productivity. However, low specific productivity still in...

    Authors: Rochelle Aw and Karen M Polizzi
    Citation: Microbial Cell Factories 2013 12:128
  10. Streptomyces, the main antibiotic-producing bacteria, responds to changing environmental conditions through a complex sensing mechanism and two-component systems (TCSs) play a crucial role in this extraordinary “...

    Authors: Héctor Rodríguez, Sergio Rico, Margarita Díaz and Ramón I Santamaría
    Citation: Microbial Cell Factories 2013 12:127
  11. Erythromycin is a medically important antibiotic, biosynthesized by the actinomycete Saccharopolyspora erythraea. Genes encoding erythromycin biosynthesis are organized in a gene cluster, spanning over 60 kbp of ...

    Authors: Benjamin Kirm, Vasilka Magdevska, Miha Tome, Marinka Horvat, Katarina Karničar, Marko Petek, Robert Vidmar, Špela Baebler, Polona Jamnik, Štefan Fujs, Jaka Horvat, Marko Fonovič, Boris Turk, Kristina Gruden, Hrvoje Petković and Gregor Kosec
    Citation: Microbial Cell Factories 2013 12:126
  12. Moths (Lepidoptera) are highly dependent on chemical communication to find a mate. Compared to conventional unselective insecticides, synthetic pheromones have successfully served to lure male moths as a speci...

    Authors: Åsa K Hagström, Hong-Lei Wang, Marjorie A Liénard, Jean-Marc Lassance, Tomas Johansson and Christer Löfstedt
    Citation: Microbial Cell Factories 2013 12:125
  13. Bacillus subtilis 168 possesses an efficient pathway to metabolize some of the stereoisomers of inositol, including myo-inositol (MI) and scyllo-inositol (SI). Previously we reported a prototype of a B. subtilis ...

    Authors: Kosei Tanaka, Shintaro Tajima, Shinji Takenaka and Ken-ichi Yoshida
    Citation: Microbial Cell Factories 2013 12:124
  14. Poly(4-hydroxybutyrate) (P4HB), belonging to the family of bacterial polyhydroxyalkanoates (PHAs), is a strong, flexible and absorbable material which has a large variety of medical applications like tissue en...

    Authors: Sylvaine Le Meur, Manfred Zinn, Thomas Egli, Linda Thöny-Meyer and Qun Ren
    Citation: Microbial Cell Factories 2013 12:123
  15. Membrane protein research is frequently hampered by the low natural abundance of these proteins in cells and typically relies on recombinant gene expression. Different expression systems, like mammalian cells,...

    Authors: Mouna Guerfal, Katrien Claes, Oskar Knittelfelder, Riet De Rycke, Sepp D Kohlwein and Nico Callewaert
    Citation: Microbial Cell Factories 2013 12:122
  16. Polyoxin, a peptidyl nucleoside antibiotic, consists of three building blocks including a nucleoside skeleton, polyoximic acid (POIA), and carbamoylpolyoxamic acid (CPOAA), however, little is known about the “...

    Authors: Wenqing Chen, Daofeng Dai, Changchun Wang, Tingting Huang, Lipeng Zhai and Zixin Deng
    Citation: Microbial Cell Factories 2013 12:121
  17. Industrial fermentations can generally be described as dynamic biotransformation processes in which microorganisms convert energy rich substrates into a desired product. The knowledge of active physiological p...

    Authors: Sandra Wiegand, Birgit Voigt, Dirk Albrecht, Johannes Bongaerts, Stefan Evers, Michael Hecker, Rolf Daniel and Heiko Liesegang
    Citation: Microbial Cell Factories 2013 12:120
  18. Isobutanol is an important target for biorefinery research as a next-generation biofuel and a building block for commodity chemical production. Metabolically engineered microbial strains to produce isobutanol ...

    Authors: Fumio Matsuda, Jun Ishii, Takashi Kondo, Kengo Ida, Hironori Tezuka and Akihiko Kondo
    Citation: Microbial Cell Factories 2013 12:119
  19. The metabolic capabilities of acetogens to ferment a wide range of sugars, to grow autotrophically on H2/CO2, and more importantly on synthesis gas (H2/CO/CO2) make them very attractive candidates as production h...

    Authors: Harish Nagarajan, Merve Sahin, Juan Nogales, Haythem Latif, Derek R Lovley, Ali Ebrahim and Karsten Zengler
    Citation: Microbial Cell Factories 2013 12:118
  20. Norleucine and norvaline belong to a group of non-canonical amino acids which are synthesized as byproducts in the branched chain amino acid metabolism of Escherichia coli. The earlier observed misincorporation o...

    Authors: Michael Biermann, Julia Linnemann, Uwe Knüpfer, Sebastian Vollstädt, Bettina Bardl, Guido Seidel and Uwe Horn
    Citation: Microbial Cell Factories 2013 12:116
  21. A number of valuable candidates as tuberculosis vaccine have been reported, some of which have already entered clinical trials. The new vaccines, especially subunit vaccines, need multiple administrations in o...

    Authors: Luciano Piubelli, Manuela Campa, Caterina Temporini, Elisa Binda, Francesca Mangione, Massimo Amicosante, Marco Terreni, Flavia Marinelli and Loredano Pollegioni
    Citation: Microbial Cell Factories 2013 12:115
  22. To cope with environmental challenges bacteria possess sophisticated defense mechanisms that involve stress-induced adaptive responses. The canonical stress regulators CtsR and HrcA play a central role in the ...

    Authors: Hermien Van Bokhorst-van de Veen, Roger S Bongers, Michiel Wels, Peter A Bron and Michiel Kleerebezem
    Citation: Microbial Cell Factories 2013 12:112
  23. Hepatitis C virus (HCV) is a common and leading cause for liver cirrhosis and hepatocellular carcinoma. Current therapies to treat HCV infection are shown to be partially effective and poorly tolerated. Theref...

    Authors: Muhammad Ikram Anwar, Mazhar Iqbal, Mohammad S Yousef and Moazur Rahman
    Citation: Microbial Cell Factories 2013 12:111
  24. The stabilizing and function-preserving effects of ectoines have attracted considerable biotechnological interest up to industrial scale processes for their production. These rely on the release of ectoines fr...

    Authors: Judith Becker, Rudolf Schäfer, Michael Kohlstedt, Björn J Harder, Nicole S Borchert, Nadine Stöveken, Erhard Bremer and Christoph Wittmann
    Citation: Microbial Cell Factories 2013 12:110
  25. Heterotrophic fermentation using simple sugars such as glucose is an established and cost-effective method for synthesizing bioproducts from bacteria, yeast and algae. Organisms incapable of metabolizing gluco...

    Authors: Yuting Zheng, Andrew H Quinn and Ganesh Sriram
    Citation: Microbial Cell Factories 2013 12:109
  26. Natural aromatic polymers, mainly melanins, have potential and current applications in the cosmetic, pharmaceutical and chemical industries. The biotechnological production of this class of compounds is based ...

    Authors: María I Chávez-Béjar, Victor E Balderas-Hernandez, Aída Gutiérrez-Alejandre, Alfredo Martinez, Francisco Bolívar and Guillermo Gosset
    Citation: Microbial Cell Factories 2013 12:108
  27. The chemoautotrophic bacterium Ralstonia eutropha can utilize H2/CO2 for growth under aerobic conditions. While this microbial host has great potential to be engineered to produce desired compounds (beyond polyhy...

    Authors: Changhao Bi, Peter Su, Jana Müller, Yi-Chun Yeh, Swapnil R Chhabra, Harry R Beller, Steven W Singer and Nathan J Hillson
    Citation: Microbial Cell Factories 2013 12:107
  28. Failure of colony PCRs in green microalga Chlorella vulgaris is typically attributed to the difficulty in disrupting its notoriously rigid cell walls for releasing the genetic materials and therefore the developm...

    Authors: Crystal Jing Ying Tear, Chanyuen Lim, Jinchuan Wu and Hua Zhao
    Citation: Microbial Cell Factories 2013 12:106
  29. In the last decade, several studies described the promising cytotoxic activity of fermented wheat germ towards cancer cell lines and during in vivo clinical trials. Recent data suggested that the antiproliferativ...

    Authors: Carlo Giuseppe Rizzello, Thomas Mueller, Rossana Coda, Franziska Reipsch, Luana Nionelli, José Antonio Curiel and Marco Gobbetti
    Citation: Microbial Cell Factories 2013 12:105
  30. The Gram-positive actinomycete Rhodococcus opacus is widely studied for its innate ability to store large amounts of carbon in the form of triacylglycerol (TAG). Several groups have demonstrated that R. opacus PD...

    Authors: Daniel P MacEachran and Anthony J Sinskey
    Citation: Microbial Cell Factories 2013 12:104
  31. Whole-cell redox biocatalysis has been intensively explored for the production of valuable compounds because excellent selectivity is routinely achieved. Although the cellular cofactor level, redox state and t...

    Authors: Yongjin J Zhou, Wei Yang, Lei Wang, Zhiwei Zhu, Sufang Zhang and Zongbao K Zhao
    Citation: Microbial Cell Factories 2013 12:103
  32. Microbial cell population heterogeneity is now recognized as a major source of issues in the development and optimization of bioprocesses. Even if single cell technologies are available for the study of microb...

    Authors: Alison Brognaux, Shanshan Han, Søren J Sørensen, Frédéric Lebeau, Philippe Thonart and Frank Delvigne
    Citation: Microbial Cell Factories 2013 12:100
  33. Rewiring and optimization of metabolic networks to enable the production of commercially valuable chemicals is a central goal of metabolic engineering. This prospect is challenged by the complexity of metaboli...

    Authors: Andrew Garst, Michael Lynch, Ron Evans and Ryan T Gill
    Citation: Microbial Cell Factories 2013 12:99
  34. Mucosal infections are a major global health problem and it is generally accepted that mucosal vaccination strategies, able to block infection at their entry site, would be preferable with respect to other pre...

    Authors: Rachele Isticato, Teja Sirec, Lucia Treppiccione, Francesco Maurano, Maurilio De Felice, Mauro Rossi and Ezio Ricca
    Citation: Microbial Cell Factories 2013 12:98
  35. For their application in the area of diagnosis and therapy, single-domain antibodies (sdAbs) offer multiple advantages over conventional antibodies and fragments thereof in terms of size, stability, solubility...

    Authors: Kristof Zarschler, Stefanie Witecy, Franz Kapplusch, Christian Foerster and Holger Stephan
    Citation: Microbial Cell Factories 2013 12:97
  36. Manipulations in Saccharomyces cerevisiae classically depend on use of auxotrophy selection markers. There are several disadvantages to this in a microbial cell factory setting: (1) auxotrophies must first be eng...

    Authors: Claudia E Vickers, Sarah F Bydder, Yuchan Zhou and Lars K Nielsen
    Citation: Microbial Cell Factories 2013 12:96
  37. Science-based recombinant bioprocess designs as well as the design of statistical experimental plans for process optimization (Design of Experiments, DoE) demand information on physiological bioprocess boundar...

    Authors: Patrick Sagmeister, Timo Langemann, Patrick Wechselberger, Andrea Meitz and Christoph Herwig
    Citation: Microbial Cell Factories 2013 12:94
  38. Given its availability and low price, glycerol derived from biodiesel industry has become an ideal feedstock for the production of fuels and chemicals. A solution to reduce the negative environmental problems ...

    Authors: Dan C Vodnar, Francisc V Dulf, Oana L Pop and Carmen Socaciu
    Citation: Microbial Cell Factories 2013 12:92
  39. Metabolic engineering has emerged as a practical alternative to conventional chemical conversion particularly in biocommodity production processes. However, this approach is often hampered by as yet unidentifi...

    Authors: Borimas Krutsakorn, Takashi Imagawa, Kohsuke Honda, Kenji Okano and Hisao Ohtake
    Citation: Microbial Cell Factories 2013 12:91
  40. After cellulose and starch, chitin is the third-most abundant biopolymer on earth. Chitin or its deacetylated derivative chitosan is a valuable product with a number of applications. It is one of the main comp...

    Authors: Youmei Xu, Mini Bajaj, Reinhard Schneider, Stephan L Grage, Anne S Ulrich, Josef Winter and Claudia Gallert
    Citation: Microbial Cell Factories 2013 12:90

Annual Journal Metrics

  • 2022 Citation Impact
    6.4 - 2-year Impact Factor
    6.3 - 5-year Impact Factor
    1.412 - SNIP (Source Normalized Impact per Paper)
    1.091 - SJR (SCImago Journal Rank)

    2023 Speed
    4 days submission to first editorial decision for all manuscripts (Median)
    75 days submission to accept (Median)

    2023 Usage 
    2,666,054 downloads
    875 Altmetric mentions