Skip to main content

Articles

Page 57 of 66

  1. Yeast expression systems with altered N-glycosylation are now available to produce glycoproteins with homogenous, defined N-glycans. However, data on the behaviour of these strains in high cell density cultiva...

    Authors: Pieter P Jacobs, Mehmet Inan, Nele Festjens, Jurgen Haustraete, Annelies Van Hecke, Roland Contreras, Michael M Meagher and Nico Callewaert
    Citation: Microbial Cell Factories 2010 9:93
  2. Escherichia coli as a frequently utilized host organism for recombinant protein production offers different cellular locations with distinct qualities. The periplasmic space is often favored for the production of...

    Authors: Thomas Heel, Michael Paal, Rainer Schneider and Bernhard Auer
    Citation: Microbial Cell Factories 2010 9:92
  3. Fumarase catalyzes the reversible hydration of fumarate to L-malate and is a key enzyme in the tricarboxylic acid (TCA) cycle and in amino acid metabolism. Fumarase is also used for the industrial production of L

    Authors: Chengjian Jiang, Lan-Lan Wu, Gao-Chao Zhao, Pei-Hong Shen, Ke Jin, Zhen-Yu Hao, Shuang-Xi Li, Ge-Fei Ma, Feng-Feng Luo, Guo-Qing Hu, Wen-Long Kang, Xing-Mei Qin, You-Li Bi, Xian-Lai Tang and Bo Wu
    Citation: Microbial Cell Factories 2010 9:91
  4. Global concerns about climate changes and their association with the use of fossil fuels have accelerated research on biological fuel production. Biological hydrogen production from hemicellulose-containing wa...

    Authors: Karin Willquist, Ahmad A Zeidan and Ed WJ van Niel
    Citation: Microbial Cell Factories 2010 9:89
  5. It is quite important to simulate the metabolic changes of a cell in response to the change in culture environment and/or specific gene knockouts particularly for the purpose of application in industry. If thi...

    Authors: Tuty Asmawaty Abdul Kadir, Ahmad A Mannan, Andrzej M Kierzek, Johnjoe McFadden and Kazuyuki Shimizu
    Citation: Microbial Cell Factories 2010 9:88
  6. Animal-free recombinant proteins provide a safe and effective alternative to tissue or serum-derived products for both therapeutic and biomanufacturing applications. While recombinant insulin and albumin alrea...

    Authors: Christopher JA Finnis, Tom Payne, Joanna Hay, Neil Dodsworth, Diane Wilkinson, Philip Morton, Malcolm J Saxton, David J Tooth, Robert W Evans, Hans Goldenberg, Barbara Scheiber-Mojdehkar, Nina Ternes and Darrell Sleep
    Citation: Microbial Cell Factories 2010 9:87
  7. The efficiency of biotechnological production processes depends on selecting the best performing microbial strain and the optimal cultivation conditions. Thus, many experiments have to be conducted, which conf...

    Authors: Matthias Funke, Andreas Buchenauer, Wilfried Mokwa, Stefanie Kluge, Lea Hein, Carsten Müller, Frank Kensy and Jochen Büchs
    Citation: Microbial Cell Factories 2010 9:86
  8. Vanillin is one of the most widely used flavouring agents, originally obtained from cured seed pods of the vanilla orchid Vanilla planifolia. Currently vanillin is mostly produced via chemical synthesis. A de nov...

    Authors: Ana Rita Brochado, Claudia Matos, Birger L Møller, Jørgen Hansen, Uffe H Mortensen and Kiran Raosaheb Patil
    Citation: Microbial Cell Factories 2010 9:84
  9. In this study, a putative esterase, designated EstMY, was isolated from an activated sludge metagenomic library. The lipolytic gene was subcloned and expressed in Escherichia coli BL21 using the pET expression sy...

    Authors: Li JunGang, Zhang KeGui and Han WenJun
    Citation: Microbial Cell Factories 2010 9:83
  10. Freezing is an increasingly important means of preservation and storage of microbial strains used for many types of industrial applications including food processing. However, the yeast mechanisms of tolerance...

    Authors: Joana Tulha, Ana Lima, Cândida Lucas and Célia Ferreira
    Citation: Microbial Cell Factories 2010 9:82
  11. In the last decades, the understanding of inclusion body biology and consequently, of their properties and potential biotechnological applications have dramatically changed. Therefore, the development of new p...

    Authors: Elena García-Fruitós
    Citation: Microbial Cell Factories 2010 9:80
  12. Acetic acid is a byproduct of Saccharomyces cerevisiae alcoholic fermentation. Together with high concentrations of ethanol and other toxic metabolites, acetic acid may contribute to fermentation arrest and reduc...

    Authors: Nuno P Mira, Margarida Palma, Joana F Guerreiro and Isabel Sá-Correia
    Citation: Microbial Cell Factories 2010 9:79
  13. The type III secretion system (T3SS) is a molecular machine in gram negative bacteria that exports proteins through both membranes to the extracellular environment. It has been previously demonstrated that the...

    Authors: Daniel M Widmaier and Christopher A Voigt
    Citation: Microbial Cell Factories 2010 9:78
  14. The benzoylformate decarboxylase (BFD) from Pseudomonas putida is a biotechnologically interesting biocatalyst. It catalyses the formation of chiral 2-hydroxy ketones, which are important building blocks for ster...

    Authors: Thomas G Palmen, Jens Nieveler, Bettina Frölich, Wiltrud Treffenfeldt, Martina Pohl and Jochen Büchs
    Citation: Microbial Cell Factories 2010 9:76
  15. The effect of high glucose concentration on the transcription levels of the small RNA SgrS and the messenger RNA ptsG, (encoding the glucose transporter IICBGlc), was studied in both E. coli K-12 (MG1655 and JM10...

    Authors: Alejandro Negrete, Weng-Ian Ng and Joseph Shiloach
    Citation: Microbial Cell Factories 2010 9:75
  16. The production of microbial lipids has attracted considerable interest during the past decade since they can be successfully used to produce biodiesel by catalyzed transesterification with short chain alcohols...

    Authors: Alberto Amaretti, Stefano Raimondi, Maurizio Sala, Lucia Roncaglia, Marzia De Lucia, Alan Leonardi and Maddalena Rossi
    Citation: Microbial Cell Factories 2010 9:73
  17. Pseudoalteromonas haloplanktis is a cold-adapted γ-proteobacterium isolated from Antarctic sea ice. It is characterized by remarkably high growth rates at low temperatures. P. haloplanktis is one of the model org...

    Authors: Boris Wilmes, Angelika Hartung, Michael Lalk, Manuel Liebeke, Thomas Schweder and Peter Neubauer
    Citation: Microbial Cell Factories 2010 9:72
  18. Bacterial inclusion bodies are submicron protein clusters usually found in recombinant bacteria that have been traditionally considered as undesirable products from protein production processes. However, being...

    Authors: Escarlata Rodríguez-Carmona, Olivia Cano-Garrido, Joaquin Seras-Franzoso, Antonio Villaverde and Elena García-Fruitós
    Citation: Microbial Cell Factories 2010 9:71
  19. Methylotrophic (methanol-utilizing) bacteria offer great potential as cell factories in the production of numerous products from biomass-derived methanol. Bio-methanol is essentially a non-food substrate, an a...

    Authors: Philipp Höfer, Young J Choi, Michael J Osborne, Carlos B Miguez, Patrick Vermette and Denis Groleau
    Citation: Microbial Cell Factories 2010 9:70
  20. The assembly and spatial organization of enzymes in naturally occurring multi-protein complexes is of paramount importance for the efficient degradation of complex polymers and biosynthesis of valuable product...

    Authors: Andrew S Wieczorek and Vincent JJ Martin
    Citation: Microbial Cell Factories 2010 9:69
  21. The formation of native disulfide bonds is a complex and essential post-translational modification for many proteins. The large scale production of these proteins can be difficult and depends on targeting the ...

    Authors: Feras Hatahet, Van Dat Nguyen, Kirsi EH Salo and Lloyd W Ruddock
    Citation: Microbial Cell Factories 2010 9:67
  22. The increasing regulatory requirements to which biological agents are subjected will have a great impact in the field of industrial protein expression and production. There is an expectation that in a near fut...

    Authors: Isabelle Peubez, Nicolas Chaudet, Charlotte Mignon, Géraldine Hild, Stéphanie Husson, Virginie Courtois, Karelle De Luca, Denis Speck and Régis Sodoyer
    Citation: Microbial Cell Factories 2010 9:65
  23. Insufficient availability of molecular chaperones is observed as a major bottleneck for proper protein folding in recombinant protein production. Therefore, co-production of selected sets of cell chaperones al...

    Authors: Mónica Martínez-Alonso, Elena García-Fruitós, Neus Ferrer-Miralles, Ursula Rinas and Antonio Villaverde
    Citation: Microbial Cell Factories 2010 9:64
  24. Overexpression of recombinant proteins usually triggers the induction of heat shock proteins that regulate aggregation and solubility of the overexpressed protein. The two-dimensional gel electrophoresis (2-DE...

    Authors: Chung-Hsien Cheng and Wen-Chien Lee
    Citation: Microbial Cell Factories 2010 9:63
  25. Fumonisin B1 is a cancerogenic mycotoxin produced by Fusarium verticillioides and other fungi. Sphingopyxis sp. MTA144 can degrade fumonisin B1, and a key enzyme in the catabolic pathway is an aminotransferase wh...

    Authors: Doris Hartinger, Stefan Heinl, Heidi Elisabeth Schwartz, Reingard Grabherr, Gerd Schatzmayr, Dietmar Haltrich and Wulf-Dieter Moll
    Citation: Microbial Cell Factories 2010 9:62
  26. Conjugate vaccines in which polysaccharide antigens are covalently linked to carrier proteins belong to the most effective and safest vaccines against bacterial pathogens. State-of-the art production of conjug...

    Authors: Julian Ihssen, Michael Kowarik, Sandro Dilettoso, Cyril Tanner, Michael Wacker and Linda Thöny-Meyer
    Citation: Microbial Cell Factories 2010 9:61
  27. Oxidative stress can severely compromise viability of bifidobacteria. Exposure of Bifidobacterium cells to oxygen causes accumulation of reactive oxygen species, mainly hydrogen peroxide, leading to cell death. I...

    Authors: Valeria Mozzetti, Franck Grattepanche, Déborah Moine, Bernard Berger, Enea Rezzonico, Leo Meile, Fabrizio Arigoni and Christophe Lacroix
    Citation: Microbial Cell Factories 2010 9:60
  28. Many workers have reported halotolerant bacteria from saline conditions capable of protease production. However, antibiotic resistance and heavy metal tolerance pattern of such organisms is not documented very...

    Authors: Sanjay K Singh, Vinayak R Tripathi, Rakesh K Jain, Surendra Vikram and Satyendra K Garg
    Citation: Microbial Cell Factories 2010 9:59
  29. To reduce the production cost of bioethanol obtained from fermentation of the sugars provided by degradation of lignocellulosic biomass (i.e., second generation bioethanol), it is necessary to screen for new enzy...

    Authors: David Navarro, Marie Couturier, Gabriela Ghizzi Damasceno da Silva, Jean-Guy Berrin, Xavier Rouau, Marcel Asther and Christophe Bignon
    Citation: Microbial Cell Factories 2010 9:58
  30. The flavin-dependent enzyme pyranose 2-oxidase (P2Ox) has gained increased attention during the last years because of a number of attractive applications for this enzyme. P2Ox is a unique biocatalyst with high...

    Authors: Clara Salaheddin, Yoshimitsu Takakura, Masako Tsunashima, Barbara Stranzinger, Oliver Spadiut, Montarop Yamabhai, Clemens K Peterbauer and Dietmar Haltrich
    Citation: Microbial Cell Factories 2010 9:57
  31. Recent years have seen a huge growth in the market of industrial yeasts with the need for strains affording better performance or to be used in new applications. Stress tolerance of commercial Saccharomyces cerev...

    Authors: Roberto Pérez-Torrado, Joaquín Panadero, María José Hernández-López, José Antonio Prieto and Francisca Randez-Gil
    Citation: Microbial Cell Factories 2010 9:56
  32. Chemical methods of producing dyes involve extreme temperatures and unsafe toxic compounds. Application of oxidizing enzymes obtained from fungal species, for example laccase, is an alternative to chemical syn...

    Authors: Jolanta Polak and Anna Jarosz-Wilkołazka
    Citation: Microbial Cell Factories 2010 9:51
  33. Pichia pastoris has been recognized as an effective host for recombinant protein production. A number of studies have been reported for improving this expression system. However, its physiology and cellular metab...

    Authors: Bevan KS Chung, Suresh Selvarasu, Andrea Camattari, Jimyoung Ryu, Hyeokweon Lee, Jungoh Ahn, Hongweon Lee and Dong-Yup Lee
    Citation: Microbial Cell Factories 2010 9:50
  34. The unfolded protein response (UPR) in eukaryotes upregulates factors that restore ER homeostasis upon protein folding stress and in yeast is activated by a non-conventional splicing of the HAC1 mRNA. The spliced...

    Authors: Mouna Guerfal, Stefan Ryckaert, Pieter P Jacobs, Paul Ameloot, Kathleen Van Craenenbroeck, Riet Derycke and Nico Callewaert
    Citation: Microbial Cell Factories 2010 9:49
  35. We describe a method for specific, quantitative and quick detection of human collagen prolyl 4-hydroxylase (C-P4H), the key enzyme for collagen prolyl-4 hydroxylation, in crude samples based on a sandwich ELIS...

    Authors: Ekaterina Osmekhina, Antje Neubauer, Katharina Klinzing, Johanna Myllyharju and Peter Neubauer
    Citation: Microbial Cell Factories 2010 9:48
  36. Recombinant protein production is universally employed as a solution to obtain the milligram to gram quantities of a given protein required for applications as diverse as structural genomics and biopharmaceuti...

    Authors: Cecilia Ferndahl, Nicklas Bonander, Christel Logez, Renaud Wagner, Lena Gustafsson, Christer Larsson, Kristina Hedfalk, Richard AJ Darby and Roslyn M Bill
    Citation: Microbial Cell Factories 2010 9:47
  37. Hyaluronic acid is one of the biopolymers most commonly used by the pharmaceutical industry. Thus, there is an increasing number of recent works that deal with the production of microbial hyaluronic acid. Diff...

    Authors: José A Vázquez, María I Montemayor, Javier Fraguas and Miguel A Murado
    Citation: Microbial Cell Factories 2010 9:46
  38. The production of stable and soluble proteins is one of the most important steps prior to structural and functional studies of biological importance. We investigated the parallel production in a medium through...

    Authors: Agnès Groisillier, Cécile Hervé, Alexandra Jeudy, Etienne Rebuffet, Pierre F Pluchon, Yann Chevolot, Didier Flament, Claire Geslin, Isabel M Morgado, Déborah Power, Margherita Branno, Hervé Moreau, Gurvan Michel, Catherine Boyen and Mirjam Czjzek
    Citation: Microbial Cell Factories 2010 9:45
  39. A bacterial artificial chromosomal library of Planobispora rosea, a genetically intractable actinomycete strain, was constructed using Escherichia coli-Streptomyces artificial chromosome (ESAC) and screened for t...

    Authors: Anna Giardina, Rosa Alduina, Elvira Gottardi, Valentina Di Caro, Roderich D Süssmuth and Anna M Puglia
    Citation: Microbial Cell Factories 2010 9:44

Annual Journal Metrics

  • 2022 Citation Impact
    6.4 - 2-year Impact Factor
    6.3 - 5-year Impact Factor
    1.412 - SNIP (Source Normalized Impact per Paper)
    1.091 - SJR (SCImago Journal Rank)

    2023 Speed
    4 days submission to first editorial decision for all manuscripts (Median)
    75 days submission to accept (Median)

    2023 Usage 
    2,666,054 downloads
    875 Altmetric mentions