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  1. Content type: Research

    Successful application of growth inhibition techniques for quantitative determination of bacteriocins relies on the sensitivity of the applied indicator microorganism to the bacteriocin to which is exposed. Ho...

    Authors: Maria Papagianni, Nicholaos Avramidis, George Filioussis, Despina Dasiou and Ioannis Ambrosiadis

    Citation: Microbial Cell Factories 2006 5:30

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  2. Content type: Research

    RecA is a highly conserved prokaryotic protein that not only plays several important roles connected to DNA metabolism but also affects the cell response to various stress conditions. While RecA is highly cons...

    Authors: Gabriele Giliberti, Loredana Baccigalupi, Angelina Cordone, Ezio Ricca and Maurilio De Felice

    Citation: Microbial Cell Factories 2006 5:29

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  3. Content type: Research

    The yields of soluble recombinant proteins expressed in bacteria are often low due to the tendency of the heterologous proteins to form aggregates. Therefore, aggregation reporters have been envisaged to simpl...

    Authors: Tina Schultz, Lucia Martinez and Ario de Marco

    Citation: Microbial Cell Factories 2006 5:28

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  4. Content type: Research

    In the interest of generating large amounts of recombinant protein, inducible systems have been studied to maximize both the growth of the culture and the production of foreign proteins. Even though thermo-ind...

    Authors: Marc G Aucoin, Virginie McMurray-Beaulieu, Frédéric Poulin, Eric B Boivin, Jingkui Chen, Francisc M Ardelean, Mathieu Cloutier, Young J Choi, Carlos B Miguez and Mario Jolicoeur

    Citation: Microbial Cell Factories 2006 5:27

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  5. Content type: Research

    The molecular mechanics of inclusion body formation is still far from being completely understood, specially regarding the occurrence of properly folded, protein species that exhibit natural biological activit...

    Authors: Nuria González-Montalbán, Elena García-Fruitós, Salvador Ventura, Anna Arís and Antonio Villaverde

    Citation: Microbial Cell Factories 2006 5:26

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  6. Content type: Research

    Fermentation of lignocellulosic biomass is an attractive alternative for the production of bioethanol. Traditionally, the yeast Saccharomyces cerevisiae is used in industrial ethanol fermentations. However, S. ce...

    Authors: Kaisa Karhumaa, Beate Wiedemann, Bärbel Hahn-Hägerdal, Eckhard Boles and Marie-F Gorwa-Grauslund

    Citation: Microbial Cell Factories 2006 5:18

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  7. Content type: Review

    The methylotrophic yeast Pichia pastoris has been widely reported as a suitable expression system for heterologous protein production. The use of different phenotypes under PAOX promoter, other alternative promot...

    Authors: Oriol Cos, Ramón Ramón, José Luis Montesinos and Francisco Valero

    Citation: Microbial Cell Factories 2006 5:17

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  8. Content type: Research

    Olive mill wastewater (OMW) is the aqueous effluent of olive oil producing processes. Given its high COD and content of phenols, it has to be decontaminated before being discharged. Anaerobic digestion is one ...

    Authors: Lorenzo Bertin, Maria Chiara Colao, Maurizio Ruzzi, Leonardo Marchetti and Fabio Fava

    Citation: Microbial Cell Factories 2006 5:16

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  9. Content type: Review

    The quantitative detection of low analyte concentrations in complex samples is becoming an urgent need in biomedical, food and environmental fields. Biosensors, being hybrid devices composed by a biological re...

    Authors: Rosa María Ferraz, Andrea Vera, Anna Arís and Antonio Villaverde

    Citation: Microbial Cell Factories 2006 5:15

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  10. Content type: Research

    Brucella abortus is a facultative intracellular pathogen that mainly infects cattle and humans. Current vaccines rely on live attenuated strains of B. abortus, which can revert to their pathogenic status and thus...

    Authors: Anderson Miyoshi, Luis G Bermúdez-Humarán, Luciana A Ribeiro, Yves Le Loir, Sérgio C Oliveira, Philippe Langella and Vasco Azevedo

    Citation: Microbial Cell Factories 2006 5:14

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  11. Content type: Review

    Brucella spp. are facultative intracellular pathogens that have the ability to survive and multiply in professional and non-professional phagocytes, and cause abortion in domestic animals and undulant fever in hu...

    Authors: Patrícia Gomes Cardoso, Gilson Costa Macedo, Vasco Azevedo and Sergio Costa Oliveira

    Citation: Microbial Cell Factories 2006 5:13

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  12. Content type: Review

    Due to its unique capability to analyze a large number of single cells for several parameters simultaneously, flow cytometry has changed our understanding of the behavior of cells in culture and of the populat...

    Authors: Diethard Mattanovich and Nicole Borth

    Citation: Microbial Cell Factories 2006 5:12

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  13. Content type: Research

    The biotreatability of actual-site polychlorinated biphenyl (PCB)-contaminated soils is often limited by their poor content of autochthonous pollutant-degrading microorganisms. In such cases, inoculation might...

    Authors: Sara Di Toro, Giulio Zanaroli and Fabio Fava

    Citation: Microbial Cell Factories 2006 5:11

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  14. Content type: Review

    Development of nucleic acid-based detection systems is the main focus of many research groups and high technology companies. The enormous work done in this field is particularly due to the broad versatility an...

    Authors: Magdalena Gabig-Ciminska

    Citation: Microbial Cell Factories 2006 5:9

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  15. Content type: Research

    Shake flasks are widely used because of their low price and simple handling. Many researcher are, however, not aware of the physiological consequences of oxygen limitation and substrate overflow metabolism tha...

    Authors: Antti Vasala, Johanna Panula, Monika Bollók, Lutz Illmann, Christian Hälsig and Peter Neubauer

    Citation: Microbial Cell Factories 2006 5:8

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  16. Content type: Review

    Specific complex interactions between soil bacteria belonging to Rhizobium, Sinorhizobium, Mesorhizobium, Phylorhizobium, Bradyrhizobium and Azorhizobium commonly known as rhizobia, and their host leguminous plan...

    Authors: Anna Skorupska, Monika Janczarek, Małgorzata Marczak, Andrzej Mazur and Jarosław Król

    Citation: Microbial Cell Factories 2006 5:7

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  17. Content type: Research

    Heat and cold shock response are normally considered as independent phenomena. A small amount of evidence suggests instead that interactions may exist between them in two Lactococcus strains.

    Authors: Mario Varcamonti, Slavica Arsenijevic, Luca Martirani, Daniela Fusco, Gino Naclerio and Maurilio De Felice

    Citation: Microbial Cell Factories 2006 5:6

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  18. Content type: Research

    Metabolic pathway manipulation for improving the properties and the productivity of microorganisms is becoming a well established concept. For the production of important metabolites, but also for a better und...

    Authors: Paola Branduardi, Michael Sauer, Luca De Gioia, Giuseppe Zampella, Minoska Valli, Diethard Mattanovich and Danilo Porro

    Citation: Microbial Cell Factories 2006 5:4

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  19. Content type: Research

    Although the citric acid fermentation by Aspergillus niger is one of the most important industrial microbial processes and various aspects of the fermentation appear in a very large number of publications since t...

    Authors: Maria Papagianni and Michael Mattey

    Citation: Microbial Cell Factories 2006 5:3

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  20. Content type: Research

    In an effort to identify alternate recombinant gene expression systems in Pseudomonas fluorescens, we identified genes encoding two native metabolic pathways that were inducible with inexpensive compounds: the an...

    Authors: Diane M Retallack, Tracey C Thomas, Ying Shao, Keith L Haney, Sol M Resnick, Vincent D Lee and Charles H Squires

    Citation: Microbial Cell Factories 2006 5:1

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  21. Content type: Review

    The limited fossil fuel prompts the prospecting of various unconventional energy sources to take over the traditional fossil fuel energy source. In this respect the use of hydrogen gas is an attractive alterna...

    Authors: Debajyoti Dutta, Debojyoti De, Surabhi Chaudhuri and Sanjoy K Bhattacharya

    Citation: Microbial Cell Factories 2005 4:36

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  22. Content type: Research

    Production of heterologous proteins in the E. coli periplasm, or into the extracellular fluid has many advantages; therefore naturally occurring signal peptides are selected for proteins translocation. The aim of...

    Authors: Rigini M Papi, Sotiria A Chaitidou, Fotini A Trikka and Dimitrios A Kyriakidis

    Citation: Microbial Cell Factories 2005 4:35

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  23. Content type: Research

    The solubility of recombinant proteins expressed in bacteria is often disappointingly low. Several strategies have been developed to improve the yield and one of the most common strategies is the fusion of the...

    Authors: Annett Dümmler, Ann-Marie Lawrence and Ario de Marco

    Citation: Microbial Cell Factories 2005 4:34

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  24. Content type: Review

    The composition of cultivation media in relation to strain development for industrial application is reviewed. Heterologous protein production and pentose utilization by Saccharomyces cerevisiae are used to illus...

    Authors: Bärbel Hahn-Hägerdal, Kaisa Karhumaa, Christer U Larsson, Marie Gorwa-Grauslund, Johann Görgens and Willem H van Zyl

    Citation: Microbial Cell Factories 2005 4:31

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  25. Content type: Research

    One of the most fascinating properties of the biotechnologically important organism Saccharomyces cerevisiae is its ability to perform simultaneous respiration and fermentation at high growth rate even under full...

    Authors: Oliver Frick and Christoph Wittmann

    Citation: Microbial Cell Factories 2005 4:30

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  26. Content type: Research

    Native as well as recombinant bacterial cell surface layer (S-layer) protein of Geobacillus (G.) stearothermophilus ATCC 12980 assembles to supramolecular structures with an oblique symmetry. Upon expression in E...

    Authors: Andreas Blecha, Kristof Zarschler, Klaas A Sjollema, Marten Veenhuis and Gerhard Rödel

    Citation: Microbial Cell Factories 2005 4:28

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  27. Content type: Research

    Many enzymes of industrial interest are not in the market since they are bio-produced as bacterial inclusion bodies, believed to be biologically inert aggregates of insoluble protein.

    Authors: Elena García-Fruitós, Nuria González-Montalbán, Montse Morell, Andrea Vera, Rosa María Ferraz, Anna Arís, Salvador Ventura and Antonio Villaverde

    Citation: Microbial Cell Factories 2005 4:27

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  28. Content type: Review

    In 1990 a new approach for vaccination was invented involving injection of plasmid DNA in vivo, which elicits an immune response to the encoded protein. DNA vaccination can overcome most disadvantages of conventi...

    Authors: Jacob Glenting and Stephen Wessels

    Citation: Microbial Cell Factories 2005 4:26

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  29. Content type: Review

    This article describes the use of biofilm reactors for the production of various chemicals by fermentation and wastewater treatment. Biofilm formation is a natural process where microbial cells attach to the s...

    Authors: Nasib Qureshi, Bassam A Annous, Thaddeus C Ezeji, Patrick Karcher and Ian S Maddox

    Citation: Microbial Cell Factories 2005 4:24

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  30. Content type: Review

    Reduced protein stability in vivo is a prerequisite to aggregation. While this is merely a nuisance factor in recombinant protein production, it holds a serious impact for man. This review focuses on specific app...

    Authors: Zoya Ignatova

    Citation: Microbial Cell Factories 2005 4:23

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  31. Content type: Research

    The availability of suitable recombinant protein is still a major bottleneck in protein structure analysis. The Protein Structure Factory, part of the international structural genomics initiative, targets huma...

    Authors: Konrad Büssow, Christoph Scheich, Volker Sievert, Ulrich Harttig, Jörg Schultz, Bernd Simon, Peer Bork, Hans Lehrach and Udo Heinemann

    Citation: Microbial Cell Factories 2005 4:21

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