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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Mucosal immunization with Lactiplantibacillus plantarum-displaying recombinant SARS-CoV-2 epitopes on the surface induces humoral and mucosal immune responses in mice

Fig. 5

Cytokine responses of sera from mice immunized with surface displayed SARS-CoV-2 epitopes and wild type L. plantarum SK156. (A) Pro-inflammatory cytokines; (B) Anti-inflammatory cytokines; (C) Ratio of anti-inflammatory and pro-inflammatory. ‘*’ indicates the results of among the epitope groups, a group significantly increased compared to other groups (ANOVA test, *p < 0.01; **p < 0.001; ***p < 0.0001). ‘■’indicates the results of significance testing for the epitope groups versus the no treatment group

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