Fig. 1
From: Biosensor-guided rapid screening for improved recombinant protein secretion in Pichia pastoris
Biosensor design and folding in the endoplasmic reticulum. Schematics of the genetic design and folding of biosensor fragments upon recombinant protein production. a, Genetic design of biosensor fragment targeted to the endoplasmic reticulum and tagged recombinant protein with secretion signal. b, Complete biosensor folding in the endoplasmic reticulum and mechanism of fluorescence increase by accumulation of recombinant protein