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Fig. 7 | Microbial Cell Factories

Fig. 7

From: Effects of branched-chain amino acids on Shiraia perylenequinone production in mycelium cultures

Fig. 7

Effect of l-Val or l-Leu on the expression of perylenequinone biosynthetic genes of S. bambusicola S8. A The proposed perylenequinone biosynthesis pathway. Some of steps and compounds are omitted for simplification. B The expression of perylenequinone biosynthetic genes by l-Val or l-Leu added at 1.5 g/L on day 2. The culture without l-Val and l-Leu in the production medium with Triton X-100 was used as control. PKS polyketide synthase, Omef O-methyltransferase, FAD FAD/FMN-dependent oxidoreductase, Mono monooxygenase, MCO multicopper oxidase, MFS major facilitator superfamily, ABC ATP-binding cassette transporter and ZFTF zinc finger transcription factor. Values are mean ± SD from three independent experiments (∗p < 0.05, ∗∗p < 0.01 versus control group)

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